Paediatric and Teenage Nutrition

food, feeding and nutrition

Category: Infants (Page 2 of 2)

treatment options for cow’s milk allergy

Treatment options for cow’s milk allergy is the 3rd in this 5-part blog series on non-IgE Cow’s Milk Allergy in Infancy and is best read following confirming a diagnosis of cow’s milk allergy.

 

Treatment options for cow’s milk allergy in infancy depend on the severity of symptoms and whether breast, formula or combination feeding is the preferred choice for parents.  An allergy focused clinical history taken by a GP or Paediatric Dietitian, will have the key information on which the best treatment options for cow’s milk allergy can be considered for both mum and baby.

Considerations

  • Breast feeding the cow’s milk allergic infant
  • Supplementary calcium, iodine and Vitamin D for mum
  • Advantages of continuing breast feeding for mum and baby
  • Alternative formulas for the cow’s milk allergic infant
  • First line prescription formulas
  • Symptoms requiring a more specialised formula

Breast feeding the cow’s milk allergic infant
Breast feeding can safely continue in the knowledge that it is protective for the allergic infant, with many advantages.  But it’s not without it’s challenges! Strict avoidance of all cow’s milk and it products, including the small amounts hidden in foods, will resolve the symptoms.  Mum needs to follow a well-balanced but strictly cow’s milk free diet at a time when her needs for nutrition are especially high. The widely available range of milks such as soya, oat, rice and nut milks are low in nutritional value and make a poor contribution to mums’ nutritional needs.  Mum needs to be committed and knowledgeable about her own needs.  For mums whose weight is low or who struggle to eat enough, or for mums who are having difficulty coping should seek further advice if they wish to continue breast feeding.  For babies with severe atopic eczema and poor weight gain, a formula milk should be considered.

Nutrition for mum and baby
Cow’s milk (and it’s products) are the principal source of calcium and iodine in UK diets, with needs increased during pregnancy and lactation by around 50-66%. Calcium is of central importance for women’s bone health and iodine for foetal and infant brain development and function.  Vitamin D is limited in foods but essential to ensure calcium is absorbed into bone and together with calcium and iodine should be taken in supplement form.

Breastfeeding Pros for baby Pros for mum
  • Improved immune development
  • Reduced incidence of ear, gut and respiratory infections
  • Enhanced tolerance to new foods
  • Enhanced taste development, facilitating broader weaning foods
  • Development of varied Microbiome, enhancing immune development
  • Bonding with baby
  • Helpful in return to pre-pregnancy weight
  • Reduction in breast cancer risk
  • Convenience and low cost
  • Bonding with baby

Alternative formulas for the cow’s milk allergic infant
Soya or goats milk formula are not recommended as treatment options for cow’s milk allergy in infants: 50 – 66% of infants will have immune reactions similar to those in cow’s milk allergy. Broadly, two types of formula are available as treatment options for cow’s milk allergy in infancy – peptide (EHF) or amino acid (AA).   The first treatment option is an extensively hydrolysed formula (EHF), in which the proteins are hydrolysed, “digested” or  broken down into short chains called peptides. The immune system does not recognise these peptides as cow’s milk protein in 90-95% of infants with non-IgE CMA, and the EHF is well tolerated.  There are a variety of EHF types and brands available on prescription, subtely suited to different needs, and is one area of a Paediatric Dietitian’s expertise.  Current EHF formulas are available with or without lactose (the milk sugar); casein (curds) or whey based protein; first or second (follow-on) milks with added iron and calcium.  Lactose has the advantage of making the formula taste better, but may not be well tolerated in infants with delayed diagnosis. Whey based formulas tend to empty from a baby’s tummy more quickly and may help improve symptoms of reflux. Second or follow-on milks are only suited for babies over 6 months.

Symptoms requiring a more specialised formula
For infants who develop symptoms of cow’s milk allergy during exclusive breast feeding, have severe symptoms or who are symptomatic following a 2-4 week trial on an EHF, an amino acid formula (AA) is indicated.  Proteins in this type of formula are further broken down from peptide chains into individual units called amino acids and are well tolerated by almost all infants.  As an expensive option (£30 per tin) careful consideration is given to its prescription.

Next Positive Outcomes for Cow’s Milk Allergy

confirming a diagnosis of cow’s milk allergy

Confirming a diagnosis of Cow’s Milk Allergy is the 2nd in this 5-part blog series about Cow’s Milk Allergy in Infancy and is best read following identifying the symptoms of cow’s milk allergy.

Common symptoms of CMA eg. loose stools, pain/colic and reflux frequently occur in babies without CMA.  This makes the diagnosis a bit tricky.  CMA is more likely when there are at least two significant problems present which impact the baby’s wellbeing, growth or feeding.  In the absence of reliable tests, the following diagnostic pathway is used by GP’s, Paediatricians and Paediatric Dietitians in order to confirm (or exclude) a diagnosis of cow’s milk allergy.

  1. An allergy focused clinical history including questions about family and individual atopy (eczema, asthma, hayfever), infants feeding and growth history, signs and symptoms focused on the gut, skin and respiratory systems, details of previous management.
  2. If the history is suggestive of Cow’s Milk Allergy, determination of whether symptoms are likely to be IgE (immediate) or non-IgE (delayed) and referral for allergy tests if IgE suspected.  The severity and timing of reactions being important. A 2-4 week trial of a strict cow’s milk exclusion diet with suitable formula, or maternal avoidance if breast feeding, with advice on supplementation of 1000mg Calcium + 10ug Vitamin D.
  3. Resolution of symptoms during the exclusion followed by obvious and confirmed relapse on re-introduction (formula or maternal consumption if breast-feeding) confirms the diagnosis.
  4. A diagnosis can only be made following a planned reintroduction of cow’s milk, which has resulted in the relapse of symptoms, mostly commonly in in 4 out of 5 infants following this diagnostic pathway.

Confirming a diagnosis of cow’s milk allergy in a timely manners and ensuring the most appropriate treatment and support is important for a variety of reasons.  For non-IgE CMA (delayed reactions) – gut symptoms resolve, pooh habits improve, tummy’s are more comfortable, eczema improves, feed volumes increase, infants are happier feeding, positive associations with feeding are made.  All of which support growth & feeding development, which in turn makes the next steps in feeding ie. weaning to solids, run much more smoothly.  Sleep is improved for all and parents anxiety is reduced – mostly!  So, just a few things then! Timely treatment also reduces risks to the baby of developing other food allergies, which are related to the presence of atopic conditions such as infant eczema.

Non-IgE Cow’s Milk Allergy is the first and most common food allergy to develop, affecting around 5% of infants in the UK, both in exclusively breast-fed and bottle-fed babies, and usually treated by the GP.  A diagnosis can be made anytime during the first year, and will depend on the severity of symptoms, other co-exisiting conditions eg. eczema and feeding or growth related difficulties.

Next Treatment options for Cow’s Milk Allergy

 

identifying the symptoms of cow’s milk allergy

Identifying the symptoms of Cow’s Milk Allergy is the 1st part in this 5-part blog series about Cow’s Milk Allergy in Infancy.

Cow’s Milk Allergy (CMA) is an immune reaction to the proteins found in cow’s milk affecting 1 in 20 infants in the UK.  There are two distinct types of cow’s milk allergy: IgE reactions with immediate onset of symptoms and non IgE reactions with delayed onset.  In both types, symptoms range from mild-moderate to severe and persisting with potentially life-threatening reactions such as anaphylaxis. The following table will help you in identifying the symptoms of Cow’s Milk Allergy.

Delayed Onset Symptoms

Non-IgE Cow’s Milk Allergy

2 – 72 hours after milk intake

Immediate Onset Reactions

IgE Cow’s Milk Allergy

Minutes after milk intake

Affecting formula-fed, exclusively breast fed infants or at the onset of mixed feeding/solids Affecting formula-fed infants or at the onset of mixed feeding
Gastrointestinal symptoms may be mild-moderate or severe and persisting
colic, reflux, loose, frequent stools, soft stool constipation, painful wind,  blood or mucous in nappy, food refusal, feeding aversion, poor growth vomiting, diarrhoea, colic
Skin symptoms can be mild-moderate or severe and persisting
itchy, raised red rash, atopic eczema intense itching, erythema (raised red rash), urticaria (flushing, spreading rash), flare up of atopic eczema, angioedema (facial swelling)
Respiratory symptoms are confined to IgE reactions
acute rhinitis (hayfever), conjunctivitis (swelling in and around the eyes) ANAPHYLAXIS

This blog series will focus on non-IgE CMA with delayed onset, which although less severe can be more complex and difficult to diagnose.  This is due to a number of issues: the similarity to other common conditions during infancy such as colic, reflux or loose stools and also the symptoms being mistakenly treated as lactose intolerance. Again this is due to the similarity in gut symptoms such as colic, bloating, discomfort and diarrhoea.  Unlike IgE CMA, there is no diagnostic allergy test for non IgE CMA and because reactions are delayed up to 72 hours after intake, cause and effect is not quite so clear. Lactose intolerance does not involve immune reactions, but results from lack of the digestive enzyme lactase, with malabsorption of the “milk sugar” lactose  causing discomfort and diarrhoea. A lactose free formula (which normally contains cow’ s milk protein) will resolve lactose intolerance but not Cow’s Milk Allergy,

Non IgE Cow’s Milk Allergy in infancy responds extremely well to prompt dietary treatment, with the majority of infants outgrowing their allergy within 6-12 months.  Delays in diagnosis and treatment lead to symptoms becoming severe and persistent, with feeding difficulties and growth faltering more evident.  Identifying the symptoms of Cow’s Milk Allergy early and discussing an allergy focused history with a trained GP or Paediatric Dietitian will assist making a diagnosis and accessing prompt appropriate treatment.

Next Confirming a diagnosis of Cow’s Milk Allergy.

a spoonful of sugar helps the porridge go down

I am now thinking about sugar in teaspoons; I am thinking 5 a day. Adults should be consuming a maximum of 30g added sugar per day, (and children 19-24g) so it depends on the size of your teaspoon; mine is quite big at 6g. A typical level spoonful is 4g; so is a sachet or a cube. A larger teaspoon or heaped is about 6g. Naturally occurring sugars are found in milk, whole fruits and vegetables and are not counted as added sugars. Added sugars are those added at home or by the manufacturer as well as those present in honey, fruit juices and syrups.

I want to keep added sugar within limits, know how much I have and of course I want to enjoy my food. Strangely, thinking in teaspoons of sugar helps me to think more positively about added sugar.

This nutritional calculation, comparing a luxury bowl of porridge to a typical sugar-ladden snack shows similar calories but very different amounts of added sugar. Perhaps it’s my Scottish roots, but I eat porridge quite often, especially when I need to be focused and work through the afternoon without feeling hungry.  Sounds dull and uninteresting? Ring the changes with some essential indulgence. This is my creamed porridge with raspberries recipe containing 1 teaspoon of added sugar.

   

Add 100mls water and 240mls whole milk to a small pot over the heat
Add 40g porridge oats and bring to the boil, then simmer for 5 minutes, stir occassionally
Pour into a bowl to cool; add a handful of frozen raspberries – pushing them into the hot porridge
Sprinkle 1 teaspoon Demerara sugar and let it melt
Drizzle 1 spoonful of double cream. YUMMY!


Nutrition Facts per portion
Creamed porridge with raspberries Can classic coke (330mls) and Snickers Bar (48g)
Calories 385kcals 384kcals
Protein 12g 4.5g
Total sugars 21g 33g
of which added 5g (1 teaspoon) 28g (> 5 teaspoons)
Fat 16g 13g
Calcium 300mg 47mg

You can see that all calories are not equal! There is similar calorie content but 5 times the amount of added sugar.  Total sugar in the porridge comes from naturally occurring sugars: lactose in the milk (11g) and fructose in the raspberries (5g).  More than twice the amount of protein, and lots of slow release carbohydrates help feelings of fullness for longer.  No sugar high – and no sugar slump!  With 6 times the amount of calcium at 300mg,  a 30% contribution to a teenagers daily needs for this essential  mineral. Oh yes, and it’s healthy for the skin, the digestive system and the brain; providing soluble fibre, prebiotics and slow-release energy for many hours.

 

the human microbiome – what do we know?

The human microbiome is our own unique ecosystem, totalling all the microbes living within our body, which amount to trillions of essential, pathogenic and opportunistic microbes including bacteria, viruses and parasites. Imagine our gut as an ecosystem, designed by nature and adapted for purpose.  It makes good use of what it consumes, recycles what it can and eliminates what it doesn’t need. This ecosystem changes over time, adapting to fixed conditions including age and gender; changing conditions such as environment or diet and others such as pathogens, illness or emotions.  Recent scientific findings show that the microbiome is of critical importance in communicating and modulating the relationship with our own unique world.  Could it be the missing link between the brain, gut and immune system?  Can we use this knowledge to improve our health and wellbeing?

Development of the microbiome starts with gut exposure to amniotic fluid in the womb, through the birth canal, the immediate environment after birth and from milk feeding.  To some extent the new infant inherits its mothers microbiome, and is also strongly influenced by early feeding and diet. It has long been known that immune benefits are conferred to breast fed babies.  More specifically, breast-fed babies have less gastrointestinal infections throughout the first two years of life, and have different species of bacterial thriving in their guts. By pre-school age, children will have a microbiome resembling adults and this will continue to change throughout life. Physiological and hormonal changes during puberty, affect the microbiome as it adapts to its changing environment.

Regular antibiotic use has a profound effect on the microbiome, having longterm effects on the balance of essential and pathogenic microbes in the gut.  This altered environment can influence many aspects of wellbeing including susceptibility to infection, food intolerance, depression, obesity and gastrointestinal problems.  Refined sugar is the single most harmful dietary ingredient for our system, not only providing empty calories and consuming essential nutrients for it utilisation, but also providing food for pathogenic microbes.  This contributes to an unfavourable balance of microbes, where pathogenic ones thrive and multiple at the expense of the essential, beneficial ones.

Want to know more about microbes? http://learn.genetics.utah.edu/content/microbiome/

 

 

 

does my child need a vitamin D supplement?

metabolism of vitamin DThis is a question many parents ask me. Multivitamin and mineral supplements should not be needed as nutrient deficiencies are rare in the UK. Provided your child is eating a variety from the 5 food groups, they are unlikely to need a vitamin supplement. The exception for this is a Vitamin D supplement. Rickets, a condition where growing bones are misshapen, is caused by Vitamin D deficiency in childhood.  It was prevalent in UK children in the early 1900’s, and is being seen increasingly in the UK again.  The reasons are multi-factorial and include less time playing outside in the sunshine, the use of sun-block because of worries about skin cancer and declining oily fish consumption.  Oily fish is the only significant dietary source of Vitamin D. More than 90% of our Vitamin D needs are met by the action of UV sun rays on the skin. Recent guidance on the need for a Vitamin D supplement from Public Health England (PHE) following a SACN review of the evidence on Vitamin D and Health says

“Children aged 1 to 4 years should have a daily 10 microgram vitamin D supplement. PHE recommends that babies are exclusively breastfed until around 6 months of age. As a precaution, all babies under 1 year should have a daily 8.5 to 10 microgram vitamin D supplement to ensure they get enough. Children who have more than 500ml of infant formula a day do not need any additional vitamin D as formula is already fortified.”

Sure Start vitamins containing Vitamin D are available for all children under 4.  Pregnant and breast feeding mums should also remember to take a Vitamin D supplement containing a minimum of 10ug daily.

weaning matters – does the mess bother you?

 

Weaning babies can be a messy time.  Learning new self feeding skills is an important part of developing the relationship with food.  It helps infants to become more independent, allows them time to explore textures and allows them take things at their own pace.  The more infants practice self-feeding, the better they will become at it.

Some parents find the mess difficult and inadvertently restrict their child from self-feeding in order to reduce mess. There is a limit for most people; we discuss this in more detail on our weaning workshops with a range of other practical aspects of feeding.

Cambridge Paediatrics and Nutrition ran its first weaning matters workshop in May 2016, and further workshops are planned this Autumn.  Details as follows:

8th October 2016 at St Andrews Hall, Histon
26th November 2016 at The Signal Box, Cambridge
7th January 2017 at The Pavillion Community Centre, Trumpington

The workshops aim to equip families with the most up-to-date information on infant feeding, weaning and feeding diffficulties in this 2 hour interactive workshop. Weaning matters will be delivered by our team of professionals: Paediatric Gastroenterologist, Speech and Language Therapist, Clinical Psychologist and Paediatric Dietitian helping parents and families to grow a healthy eater.

Short talks by each of our our team with practical demonstrations starting at 10am.

  • Growth & Development Overview
    • Camilla Salvestrini, Paediatric Gastroenterologist
  • Foods and Nutrition: What, when and how much?
    • Carine Henry, Paediatric Dietitian
  • Skills & Communication: “I know what I can do, I know what I like”
    • Cathy Davies, Speech and Language Therapist
  • Weaning & the family: Taking the worry out of weaning
    • Caroline Lindsay, Clinical Psychologist

For further information or to book, please contact us at weaning@paediatricnutrition.com

Newer posts »